Related topics: genes · dna sequences · chromosomes

Gene-silencing complexes join forces to inactivate X chromosomes

RIKEN researchers have shed new light on the roles two protein complexes play in the enigmatic process of turning off one X chromosome in female mammals. This finding could help researchers discover how certain cancers occur ...

Novel sex-determination mechanism revealed in mammals

In mammals, the distinction between male and female at the chromosomal level is due to the X and Y chromosomes. Typically, females have two X chromosomes (XX) while males have an X and a Y chromosome (XY). The Sry gene on ...

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Y chromosome

The Y chromosome is the sex-determining chromosome in most mammals, including humans. In mammals, it contains the gene SRY, which triggers testis development, thus determining sex. The human Y chromosome is composed of about 60 million base pairs.

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