Scientists excise vector, exotic genes from induced stem cells
A team of University of Wisconsin-Madison researchers reports that it has created induced human pluripotent stem (iPS) cells completely free of viral vectors and exotic genes.
A team of University of Wisconsin-Madison researchers reports that it has created induced human pluripotent stem (iPS) cells completely free of viral vectors and exotic genes.
Cell & Microbiology
Mar 26, 2009
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Lipid nanoparticles (SLNs and NLCs) are regarded as highly promising systems for delivering nucleic acids in gene therapy. Until now, viral systems have been the most effective method for delivering genetic matter but they ...
Bio & Medicine
Feb 14, 2017
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UCLA scientists have identified a protein that plays a critical role in regulating human blood stem cell self-renewal by helping them sense and interpret signals from their environment.
Cell & Microbiology
Jun 5, 2024
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A team of researchers from the Institute of Plant Molecular and Cellular Biology (IBMCP), mixed center of the Polytechnic University of Valencia (UPV) and the Spanish National Research Council (CSIC), has taken another step ...
Biotechnology
Feb 8, 2021
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Gene transfer is seen as a hopeful therapy for Alzheimer's and Parkinson's patients. The approach involves using harmless laboratory-produced viruses to introduce important genes into the brain cells. In a study on mice, ...
Cell & Microbiology
Jun 16, 2017
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Researchers at the Polytechnic Institute of New York University (NYU-Poly) and the NYU College of Dentistry (NYUCD) have developed a carrier in their lab that is five times more efficient in delivering DNA into cells than ...
Biochemistry
Dec 16, 2013
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Viral vectors hold much potential for gene editing and gene therapy, but there is a pressing need to develop quality control methods to minimize potential side effects on patients. Addressing this, researchers from Japan ...
Bio & Medicine
Aug 1, 2024
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The ability to insert desirable genes into animal or human cells is the basis of modern life science research and of widespread biomedical applications. The methods used to date for this purpose are mostly non-specific, making ...
Biotechnology
Jun 17, 2021
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Dogs have been faithful human companions ever since their domestication thousands of years ago. With improvements in veterinary medicine in recent decades, their life expectancy has increased. However, an unfortunate side ...
Molecular & Computational biology
Feb 3, 2021
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With harvest in full swing, many farmers have found that the brutal combination of high winds, scorching temperatures and minimal rainfall has left most wheat yields looking less like the good or the bad and more like the ...
Biotechnology
Jun 22, 2011
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