Breaking COVID-19's 'clutch' to stop its spread

Scripps Research chemist Matthew Disney, Ph.D., and colleagues have created drug-like compounds that, in human cell studies, bind and destroy the pandemic coronavirus' so-called "frameshifting element" to stop the virus from ...

Pulling the plug on the coronavirus copy machine

Key proteins used by coronavirus for its reproduction being modeled on NSF-funded Frontera supercomputer by Andres Cisneros research group of the University of North Texas. Research goals include finding ways to improve on ...

Mechanism discovered how the coronavirus hijacks the cell

Researchers at ETH Zurich and the University of Bern have discovered a mechanism by which the corona virus manipulates human cells to ensure its own replication. This knowledge will help to develop drugs and vaccines against ...

Scientists uncover pivotal virus structure for replication

Researchers from the Monash Biomedicine Discovery Institute (BDI) have revealed the structure of a protein complex that is essential for the poliovirus to replicate. The structure may be similar to those in other RNA viruses ...

New method captures early viral-host protein interactions

More than 70% of all viruses known to cause human disease, including the one that causes COVID-19, are RNA viruses. They invade the body by hijacking the internal machinery of cells. Yet little is known about how viral RNA ...

Making sense of the viral multiverse

In November of 2019—likely, even earlier—a tiny entity measuring just a few hundred billionths of a meter in diameter began to tear apart human society on a global scale. Within a few months, the relentless voyager known ...

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