Targeting Nsp1 protein could be a pathway for COVID-19 therapy
A study that identifies how a coronavirus protein called Nsp1 blocks the activity of genes that promote viral replication provides hope for new COVID-19 treatments.
A study that identifies how a coronavirus protein called Nsp1 blocks the activity of genes that promote viral replication provides hope for new COVID-19 treatments.
Molecular & Computational biology
Feb 16, 2021
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28
A group of scientists led by EMBL's Mikhail Savitski, Nassos Typas, and Pedro Beltrao, and collaborator Steeve Boulant at Heidelberg University Hospital, have analyzed how the novel coronavirus affects proteins in human cells. ...
Cell & Microbiology
Feb 16, 2021
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5
A chemical probe molecule—a "first gen" molecule that can be used for drug development—that targets a host cell's protein quality control pathways can dramatically reduce infection by Dengue and Zika viruses. The research ...
Cell & Microbiology
Jan 27, 2021
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As the global coronavirus pandemic continues, scientists are not only trying to find vaccines and drugs to combat it, but also to continuously learn more about the virus itself. "By now we can expect the coronavirus to become ...
Cell & Microbiology
Nov 23, 2020
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196
Researchers at ETH Zurich and the University of Bern have discovered a mechanism by which the corona virus manipulates human cells to ensure its own replication. This knowledge will help to develop drugs and vaccines against ...
Cell & Microbiology
Sep 14, 2020
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112
Many viruses, including HIV and influenza A, mutate so quickly that identifying effective vaccines or treatments is like trying to hit a moving target. A better understanding of viral propagation and evolution in single cells ...
Biochemistry
Aug 20, 2020
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175
A protein that is critical for retrovirus replication may select viral genetic material for packaging within the nuclei of host cells, rather than in the cytoplasm, as was previously believed. The research, led by a team ...
Cell & Microbiology
Jul 30, 2020
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70
After eluding researchers for more than 30 years, the VP3 protein of rotavirus has finally revealed its unique structure and function to a team led by scientists at Baylor College of Medicine. The researchers discovered that ...
Cell & Microbiology
Apr 16, 2020
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Viruses—small disease-causing parasites that can infect all types of life forms—have been well studied, but many mysteries linger. One such mystery is how a spherical virus circumvents energy barriers to form symmetric ...
Bio & Medicine
Mar 9, 2020
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A Rutgers-led team has developed a tool to monitor influenza A virus mutations in real time, which could help virologists learn how to stop viruses from replicating.
Biochemistry
Feb 6, 2020
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26