Influenza virus-induced oxidized DNA activates inflammasomes

Both influenza virus M2, a proton-selective ion channel essential for efficient viral replication, and PB1-F2 protein, which localizes to the mitochondria and attenuates host antiviral immunity, are involved in the inflammatory ...

Herpesvirsuses hedge their bets to optimize survival

When investors hedge a bet, they divvy their money between risky investments, which might make a large profit, and safe investments, which help ensure that not everything is lost in a market crash. The herpesvirus cytomegalovirus, ...

Experimental peptide targets COVID-19

Using computational models of protein interactions, researchers at the MIT Media Lab and Center for Bits and Atoms have designed a peptide that can bind to coronavirus proteins and shuttle them into a cellular pathway that ...

Scientists uncover pivotal virus structure for replication

Researchers from the Monash Biomedicine Discovery Institute (BDI) have revealed the structure of a protein complex that is essential for the poliovirus to replicate. The structure may be similar to those in other RNA viruses ...

New study shines light on mysterious giant viruses

In recent years, giant viruses have been unearthed in several of the world's most mysterious locations, from the thawing permafrost of Siberia to locations unknown beneath the Antarctic ice. But don't worry, "The Thing" is ...

New method captures early viral-host protein interactions

More than 70% of all viruses known to cause human disease, including the one that causes COVID-19, are RNA viruses. They invade the body by hijacking the internal machinery of cells. Yet little is known about how viral RNA ...

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