Conditions affecting the arterial vasculature present pressing challenges in global health. Yet, the complex mechanisms underlying artery formation remain elusive, impeding the development of new treatments.
Cell & Microbiology
Apr 3, 2024
0
6
FOXO1, a key transcription factor in cellular processes, governs metabolism, apoptosis, and aging. Despite its significance, the comprehensive regulation of FOXO1 in endothelial cells (EC) remains unexplored.
Cell & Microbiology
Mar 8, 2024
0
10
A microbial sensor that helps identify and fight bacterial infections also plays a key role in the development of blood stem cells, providing a valuable new insight in the effort to create patient-derived blood stem cells ...
Cell & Microbiology
Dec 19, 2023
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96
Blood vessels are responsible for the appropriate and efficient delivery of nutrients and oxygen to the whole body. To do so, they must grow and branch to reach every cell in a process called angiogenesis. The precise regulation ...
Cell & Microbiology
Nov 29, 2023
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1
Although a simple molecule, nitric oxide is an important signal substance that helps to reduce blood pressure by relaxing the blood vessels. But how it goes about doing this has long been unclear. Researchers at Karolinska ...
Biochemistry
Sep 14, 2023
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20
New research on reproductive health demonstrates the first successful delivery of mRNA to placental cells to treat preeclampsia at its root.
Bio & Medicine
Feb 15, 2023
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46
Microglia are a type of immune cell that works as a "janitor" to the central nervous system that clears out dead cells and other debris. But when these janitor cells themselves die, other microglia don't do the cleaning up ...
Cell & Microbiology
Oct 25, 2022
0
96
By systematically analyzing epigenetic changes in angiogenesis-stimulated vascular endothelial cells, Professor Takashi Minami (Kumamoto University, Japan) and his team have found a unique epigenetic modification (bivalent ...
Cell & Microbiology
Feb 8, 2022
0
40
Vascularized structures infiltrated within a nanofibrous extracellular matrix (ECM) play vital roles in maintaining functions and metabolism of tissue and organs. Nanofibrous scaffolds are promising in tissue engineering ...
Bio & Medicine
Feb 3, 2021
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16
In experiments in rats and mice, two Johns Hopkins scientists—an engineer and an ophthalmologist—report the successful use of nanoparticles to deliver gene therapy for blinding eye disease. A uniquely engineered large ...
Bio & Medicine
Jul 7, 2020
0
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