New device for identifying aggressive breast cancers

A new disposable device based on advances in microfluidics may help identify advanced breast cancer patients who are candidates for therapy with the drug trastuzumab (Herceptin). The device is described in the American Institute ...

A new model for transmembrane cell-surface receptor activation

"This 'rotation model', which made the cover of BioEssays, represents a true paradigm shift in the membrane receptor field," stated Prof. Pierre De Meyts, a renowned researcher of insulin and receptor binding for almost half ...

How microvilli form

The gut is lined by cells containing brush borders, which are composed of arrays of microvillar protrusions that help in nutrient absorption and provide a barrier against pathogens and toxins. Microbes such as E. coli can ...

Molecular scissors stabilize the cell's cytoskeleton

Researchers at the Paul Scherrer Institute PSI in Villigen, Switzerland, have for the first time elucidated the structure of important enzymes in human cells that alter essential building blocks of the cellular cytoskeleton. ...

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