Since the completion of the Human Genome Project, which identified nearly 20,000 protein-coding genes, scientists have been trying to decipher the roles of those genes. A new approach developed at MIT, the Broad Institute, ...
Biotechnology
Dec 12, 2013
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Scientists at the Friedrich Miescher Institute for Biomedical Research have identified a novel and unexpected regulatory activity of RNA at the edge of inactive chromosomal regions. In their publication in Nature Structural ...
Cell & Microbiology
Aug 8, 2013
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A particular tumor suppressor gene that fights cancer cells does more than clamp down on unabated cell division—the hallmark of the disease—it also can help make cells more fit by allowing them to fend off stress, says ...
Cell & Microbiology
May 10, 2013
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(Phys.org)—Researchers at Michigan State University have discovered a protein that does its best work with one foot in the grave.
Biochemistry
Dec 12, 2012
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Researchers have shown for the first time that the protein fortilin promotes growth of cancer cells by binding to and rendering inert protein p53, a known tumor suppressor. This finding by researchers at the University of ...
Biochemistry
Sep 16, 2011
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A cancer cell may seem out of control, growing wildly and breaking all the rules of orderly cell life and death. But amid the seeming chaos there is a balance between a cancer cell's revved-up metabolism and skyrocketing ...
Biochemistry
Jul 13, 2011
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The gene for the protein p53 is the most frequently mutated in human cancer. It encodes a tumor suppressor, and traditionally researchers have assumed that it acts primarily as a regulator of how genes are made into proteins. ...
Cell & Microbiology
Mar 2, 2011
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A protein that is crucial for regulating the self-renewal of normal prostate stem cells, needed to repair injured cells or restore normal cells killed by hormone withdrawal therapy for cancer, also aids the transformation ...
Cell & Microbiology
Dec 2, 2010
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A landmark study by Florida State University biologists, in collaboration with scientists in Britain, is the first to identify a life-or-death "cell competition" process in mammalian tissue that suppresses cancer by causing ...
Biotechnology
Jul 13, 2010
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The DNA contained within each of our cells is exactly the same, yet different types of cells - skin cells, heart cells, brain cells - perform very different functions. The ultimate fate of these cells is encoded not just ...
Cell & Microbiology
Jan 6, 2010
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