Exotic signaling mechanism in pathogens

The unicellular parasite that causes sleeping sickness differs from other eukaryotes in the mode of regulation of an essential cellular signaling pathway. This provides a promising point of attack for drug development.

Viral communications hacking boosts Leishmania infections

New research from McGill University has found that a virus infecting the Leishmania parasite spreads by exploiting a mechanism used for cell-to-cell communication, a discovery that could pave the way to new vaccines against ...

Discovery aids disease elimination efforts

Researchers at the University of Dundee have identified a new drug target in parasites that cause major neglected tropical diseases, a discovery that contributes towards a global drive to eliminate these diseases by 2030.

Sugar withdrawal—killing the leishmania parasite

Findings on how parasites cope with stress on a cellular level could aid the development of drugs that combat leishmaniasis, a tropical disease neglected by the pharmaceutical industry.

Disease poses risk to chimpanzee conservation, study finds

Infectious disease should be a key consideration in wildlife conservation, suggests a study focused on primates in Tanzania's Gombe Stream National Park, published by PLOS Neglected Tropical Diseases. The study investigated ...

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Tropical disease

Tropical diseases are diseases that are prevalent in or unique to tropical and subtropical regions. The diseases are less prevalent in temperate climates, due in part to the occurrence of a cold season, which controls the insect population by forcing hibernation. Insects such as mosquitoes and flies are by far the most common disease carrier, or vector. These insects may carry a parasite, bacterium or virus that is infectious to humans and animals. Most often disease is transmitted by an insect "bite", which causes transmission of the infectious agent through subcutaneous blood exchange. Vaccines are not available for any of the diseases listed here.

Some of the strategies for controlling tropical diseases include:

Human exploration of tropical rainforests, deforestation, rising immigration and increased international air travel and other tourism to tropical regions has led to an increased incidence of such diseases.

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