Using UT Southwestern's Cryo-Electron Microscopy Facility, researchers have captured images of an enzyme for Wnt lipidation, which is pivotal to human development and crucial for Wnt signaling activation. The findings, reported ...
Biochemistry
Aug 16, 2022
0
18
One of the most promising avenues in treating cancer is to restore our immune system's ability to recognize and attack cancerous cells. A team of University of Chicago chemists and biologists developed a tiny device that ...
Bio & Medicine
Mar 3, 2022
0
335
Cancer immunotherapy such as immune checkpoint blockade (ICB) is a revolutionary treatment against tumors by re-enforcing immune surveillance and even inducing long-term disease control.
Bio & Medicine
Sep 29, 2021
0
59
Scientists led by Dr. Salvador Aznar-Benitah, head of the Stem Cells and Cancer laboratory at IRB Barcelona, have described the alterations that occur during mammary gland formation when heterochromatin (the part of DNA that ...
Cell & Microbiology
May 18, 2021
0
14
Cisplatin has been used to treat cancer since the 1970s. Since then, many other platinum-containing cytostatic drugs have been developed, such as triplatinNC, a highly charged complex that contains three ligand-bridged platinum ...
Biochemistry
Jan 25, 2021
0
51
In an effort to address a major challenge when analyzing large single-cell RNA-sequencing datasets, researchers from The University of Texas MD Anderson Cancer Center have developed a new computational technique to accurately ...
Biotechnology
Jan 18, 2021
0
45
Imagine trying to throw a bullseye when the dartboard lies buried within a crumpled box. That's the challenge faced by scientists working to make new medicines for some 'undruggable' diseases, including a type of metastatic ...
Biochemistry
Dec 15, 2020
0
49
A longstanding quest in medicine has been to understand how the same disease presents differently among various patients. Although it has been thought that a central aspect of these differences is a heterogeneity between ...
Biotechnology
Mar 19, 2020
0
8
Some types of cancer cannot be treated with classical chemotherapy. Scientists from Inserm, CNRS, Sorbonne University, PSL university, University Grenoble Alpes and ESRF, the European Synchrotron, are working on a metallorganic ...
Biochemistry
Feb 4, 2019
0
34
Approximately 10-20 percent of diagnosed breast cancers are found to be triple-negative, meaning the breast cancer cells test negative for estrogen and progesterone receptors as well as HER2 receptors, genes that can play ...
Bio & Medicine
Oct 1, 2018
0
13
