Decoding the language of cellular messaging

Before the days of rote texting and email, if you wanted to communicate with a friend you might have personalized and assembled a physical letter. Similarly, the individual cells in our bodies communicate with each other ...

Brain receptor pulls open electrical gate like a puppet master

For the first time, researchers in the lab of CSHL Professor Hiro Furukawa have been able to track each atom in the NMDA receptor, an important brain protein, as it transmits or inhibits neural signals. Critical for brain ...

An experimental new method to study disease, including COVID-19

Yale Cancer Center (YCC) scientists have developed a new cell screening method for agents that alter biologic functions. This approach uses thousands of artificial proteins called "traptamers" and may help to answer some ...

Researchers create synthetic nanopores made from DNA

In 2015, the first commercial nanopore DNA sequencing device was introduced by Oxford Nanopore Technologies. Based on a synthetically engineered transmembrane protein, nanopore sequencing allows long DNA strands to be channelled ...

Gene for acid-sensitive ion channel identified

In the human body the salt content of cells and their surrounding is regulated by sophisticated transport systems. Special channels in the cell membrane selectively permit salt ions to flow in and out of cells. A research ...

Scientists create complex transmembrane proteins from scratch

It is now possible to create complex, custom-designed transmembrane proteins from scratch, scientists report this week. The advance, led by molecular engineers at the University of Washington Institute for Protein Design, ...

Improved model of energy highway along protein strands

Ever heard of polarons? They are a kind of quasi-particle resulting from electrons self-trapping in a vibrating crystal lattice. Polarons can be harnessed to transport energy under certain conditions related to the relative ...

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