Why do mitochondria retain their own genome?

It sounds like science fiction to suggest that every cell in the human body is occupied by a tiny genome-equipped organelle, with which we exist in symbiosis. But in actuality, eukaryotic life is dependent on mitochondria, ...

Scientists create complex transmembrane proteins from scratch

It is now possible to create complex, custom-designed transmembrane proteins from scratch, scientists report this week. The advance, led by molecular engineers at the University of Washington Institute for Protein Design, ...

'Vicious cycle' shields, spreads cancer cells

A "vicious cycle" produces mucus that protects uterine and pancreatic cancer cells and promotes their proliferation, according to researchers at Rice University. The researchers offer hope for a therapeutic solution.

Cell membrane proteins give up their secrets

Rice University scientists have succeeded in analyzing transmembrane protein folding in the same way they study the proteins' free-floating, globular cousins.

Researchers create synthetic nanopores made from DNA

In 2015, the first commercial nanopore DNA sequencing device was introduced by Oxford Nanopore Technologies. Based on a synthetically engineered transmembrane protein, nanopore sequencing allows long DNA strands to be channelled ...

Tiny channels carry big information

They say it's the little things that count, and that certainly holds true for the channels in transmembrane proteins, which are small enough to allow ions or molecules of a certain size to pass through, while keeping out ...

Assembling nanomachines in bacteria

Osaka University researchers use X-ray crystallography and electron microscopy to resolve the assembly of the export gate apparatus in Salmonella. The new details of this nanomachine are expected to clarify how bacteria infect ...

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