A promising target for new RNA therapeutics now accessible

Only recently, a new era in medicine began with the first RNA vaccines. These active substances are modified RNAs that trigger immune responses of the human immune system. Another approach in RNA medicine targets the body's ...

Weaker transcription factors are better when they work together

Bioengineers can tailor the genomes of cells to create "cellular therapies" that fight disease, but they have found it difficult to design specialized activating proteins called transcription factors that can throw the switch ...

Study shows genes are read faster and more sloppily in old age

Fast but sloppy, that's how the transcription of genes changes with age. Six research groups from the University of Cologne Cluster of Excellence on Cellular Stress Responses in Age-Associated Diseases (CECAD), the Max Planck ...

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