Transcription factor proteins are the light switches of the human genome. By binding to DNA, they help turn genes 'on' or 'off' and start the important process of copying DNA into an RNA template that acts as a blueprint ...
Biotechnology
Oct 21, 2020
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Using an approach based on CRISPR proteins, MIT researchers have developed a new way to precisely control the amount of a particular protein that is produced in mammalian cells.
Biotechnology
Nov 1, 2022
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28
The rapid scientific advancements that followed the mapping of the human genome have revealed just how staggeringly complex the world of genetics is. We now know that proteins are not just the products of genes, but that ...
Molecular & Computational biology
Oct 27, 2021
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38
Many different tissues and organs form from pluripotent stem cells during embryonic development. To date it had been known that these processes are controlled by transcription factors for specific tissues. Scientists from ...
Cell & Microbiology
Jan 29, 2013
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Like people with a big choice to make, stem cells have a process to "decide" whether to transform into a specific cell type or to stay flexible, a state that biologists call "pluripotency." Using a technology he invented, ...
Biotechnology
Apr 27, 2011
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Clay can be used in various forms for a range of objects such as cups, plates or bricks. Similarly, proteins can transform their structure and thus adapt their function and activity. Researchers at the Max Planck Institute ...
Cell & Microbiology
Oct 17, 2013
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Proteins known as transcription factors act as switches that regulate the expression of nearby genes, but the identity of some of these genetic levers has so far remained mysterious. Now, researchers from the Schübeler group ...
Biotechnology
Jul 8, 2021
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30
Scientists have found a control switch that regulates stem cell "pluripotency," the capacity of stem cells to develop into any type of cell in the human body. The discovery reveals that pluripotency is regulated by a single ...
Cell & Microbiology
Sep 15, 2011
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Researchers may be able to improve corn yields and nutritional value after discovering genetic regulators that synthesize starch and protein in the widely eaten grain, according to a Rutgers-led study.
Biotechnology
May 22, 2019
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51
For about a dozen years, synthetic biologists have been working on ways to design genetic circuits to perform novel functions such as manufacturing new drugs, producing fuel or even programming the suicide of cancer cells.
Cell & Microbiology
Aug 3, 2012
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