In a study published in the Journal of the American Chemical Society, researchers appear to have discovered a way to produce a true structure of the rare but naturally-occurring anti-HIV compound Lancilactone C from start ...
Biochemistry
Jul 28, 2023
0
21
Starting from available chemicals, a German team of researchers successfully completed the total synthesis of agarozizanol B, an interesting natural substance found in agarwood. As described in the journal Angewandte Chemie, ...
Materials Science
Oct 8, 2021
0
76
The story of halichondrin B, an inspirational molecule obtained from a marine creature, goes back to the molecule's discovery in an ocean sponge in 1986.
Materials Science
Jun 29, 2021
0
18
Scientists at Waseda University succeeded in developing a method for a total synthesis of cotylenin A, a plant growth regulator which has attracted considerable attention from the scientific community due to its promising ...
Biochemistry
May 12, 2020
0
16
In Japan, puffer fish is considered a delicacy, but the tickle to the taste buds comes with a tickle to the nerves: fugu contains tetrodotoxin, a strong nerve toxin. In low doses, tetrodotoxin is shown in clinical trials ...
Biochemistry
Mar 6, 2020
0
110
The death cap mushroom is highly toxic. However, some of its toxins can also be healing: amanitins are potential components for antibody-based cancer treatments. In the journal Angewandte Chemie, German scientists have now ...
Biochemistry
Feb 4, 2020
0
509
It's a feat three decades in the making: Harvard University chemists have achieved what a new paper calls a "landmark in drug discovery" with the total synthesis of halichondrin. Known to be a potent anti-cancer agent in ...
Biochemistry
Jun 17, 2019
1
608
Natural products, or their close derivatives, make some of our most potent medicines, among which macrocycles with their large carbon-rich ring systems are one class. The size and complexity of macrocycles has made it difficult ...
Biochemistry
Jun 11, 2019
0
3
With its vast numbers of different lifeforms, the sea is a largely unexplored source of natural products that could be starting points for new pharmaceuticals, such as the antitumor drugs trabectedin and lurbinectedin. Because ...
Materials Science
Feb 19, 2019
0
40
Fresh garlic extracts contain a variety of healthy organosulfur compounds, among which ajoene forms a major oil-extractable ingredient. Now, chemists in the United Kingdom have synthesized ajoene from readily available components ...
Materials Science
Aug 23, 2018
0
15
