Cilia-free stem cells offer new path to study rare diseases

A group of rare diseases called "ciliopathies"—polycystic kidney disease notable among them—emerge from defects in cilia, the tiny hair-like structures on the surface of almost every cell type. But the specific molecular-level ...

Mapping how cell types and tissues develop

Researchers have developed a technique that allows them to look simultaneously at a spatial level and at a genome-wide level at epigenetic mechanisms underlying tissue development, a breakthrough with multiple scientific ...

Building a human body through gastrulation

A collaboration of researchers from Japan, Spain and the U.S. offers a phylogenetic and ontogenetic overview of the primitive streak and its role in mediating amniote (vertebrate animals that develop on land) gastrulation, ...

Algae breathe life into 3-D engineered tissues

3-D bioprinted algae can be harnessed as a sustainable source of oxygen for human cells in engineered vascularized tissues, researchers report November 18 in the journal Matter. They embedded the bioprinted photosynthetic ...

Organoids produce embryonic heart

There was a time when the idea of growing organs in the lab was the stuff of science fiction. Today, stem cell biology and tissue engineering are turning fiction into reality with the advent of organoids: tiny lab-grown tissues ...

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