Delivering functional genes into cells to replace mutated genes, an approach known as gene therapy, holds potential for treating many types of diseases. The earliest efforts to deliver genes to diseased cells focused on DNA, ...
Biochemistry
Oct 16, 2018
0
71
Charcot-Marie Tooth disease is the most common hereditary neurological disease in the world. It affects the peripheral nerves and causes progressive paralysis of the legs and hands. No treatment is currently available to ...
Biotechnology
Mar 9, 2021
0
109
The Chinese Hamster Ovary (CHO) cell is one of the most preferred hosts used to manufacture therapeutic proteins -- genes that are added to "cell factories" to produce proteins that are later turned into medicines.
Biotechnology
Aug 5, 2011
0
0
There is great potential in gene therapy for treating certain types of cancer and genetic defects, immunological diseases, wounds and infections. The therapies work by delivering genes into the patients' cells, which then ...
Bio & Medicine
Oct 7, 2020
0
8
(Phys.org) —Scientists have found another chink in bacteria's armour, mapping for the first time the structure of a protein that plays an important role helping infection gain a foothold in the body.
Cell & Microbiology
Sep 2, 2013
0
0
In a paper published today in Nature Chemical Biology, a team of researchers from Uppsala University, the Broad Institute of MIT, Harvard, and AstraZeneca are presenting new insights into how larger-than-average molecules ...
Biochemistry
Oct 18, 2016
0
174
A University of Toronto Engineering research team has created a new platform that delivers multiple therapeutic proteins to the body, each at its own independently controlled rate. The innovation could help treat degenerative ...
Biochemistry
Aug 22, 2022
0
138
Vijay Pande's chemistry and structural biology group at Stanford has become known for Folding@home, a distributed computing project that borrows computing time from home computers to simulate how proteins take shape.
Computer Sciences
Nov 21, 2011
0
0
A new discovery by UNC scientists describes how cells infected by the Epstein-Barr virus (EBV) produce small vesicles or sacs called exosomes, changing their cellular "cargo" of proteins and RNA. This altered exosome enters ...
Cell & Microbiology
Nov 8, 2010
0
0
Findings of Cambridge scientists, published today in the journal PLoS Pathogens, show a new mechanism used by bacteria to spread in the body with the potential to identify targets to prevent the dissemination of the infection ...
Cell & Microbiology
Dec 6, 2012
0
0
