Scientists open up new world for biologics—inside the cell

The vast majority of top-selling drugs are biologics—also known as proteins. Proteins are used today to treat many debilitating diseases, including arthritis, Crohn's disease, and several forms of cancer. They have helped ...

'Cellular dust' provides new hope for regenerative medicine

While stem cells have the most therapeutic potential, the benefits of regenerative medicine may best be mobilised using extracellular vesicles (EVs), also known in the past as "cellular dust." A team of researchers from CNRS, ...

This RNA-based technique could make gene therapy more effective

Delivering functional genes into cells to replace mutated genes, an approach known as gene therapy, holds potential for treating many types of diseases. The earliest efforts to deliver genes to diseased cells focused on DNA, ...

Therapeutic antibodies vary depending on production system

Differences in production methods for therapeutic antibodies can lead to variations in their structure, depending on the recombinant procedure selected. The distinctions, which are based on a number of glycosylations, even ...

New innovations in cell-free biotechnology

A Northwestern University-led team has developed a new way to manufacture proteins outside of a cell that could have important implications in therapeutics and biomaterials.

Microbial murder mystery solved

Immune cells called "killer cells" target bacteria invading the body's cells, but how do they do this so effectively? Bacteria can quickly evolve resistance against antibiotics, yet it seems they have not so readily been ...

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