How DNA repair can go wrong and lead to disease

We often come to an understanding of what causes a disease. We know, for example, that cancers are caused by mutations at critical locations in the genome, resulting in loss of control of cell growth. We know that the onset ...

Some cancer cells may not be as immortal as previously thought

Scientists at Johannes Gutenberg University Mainz (JGU) and the Institute of Molecular Biology (IMB) in Mainz may have discovered new insights into how cancer cells regulate the ends of their chromosomes, called telomeres. ...

How much (DNA) damage can a cancer cell tolerate?

A new study led by Claus M. Azzalin, group leader at Instituto de Medicina Molecular João Lobo Antunes- iMM and published today in the Proceedings of the National Academy of Sciences (PNAS) shows, for the first time, that ...

Can we live longer? Physicist makes discovery about telomeres

With the aid of physics and a minuscule magnet, researchers have discovered a new structure of telomeric DNA. Telomeres are sometimes seen as the key to living longer. They protect genes from damage but get a bit shorter ...

Climate warming damages DNA of endangered songbirds

Extreme heat waves can cause birds and mammals to die en masse. But it's more common for an animal to experience relatively mild heat stress that doesn't kill it. Our new findings suggest that unfortunately, these individuals ...

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