A research team led by Nagoya University scientists in Japan has developed an approach that can quickly find synthetic proteins that specifically bind to important targets, such as components of the SARS-CoV-2 virus. The ...
Biochemistry
Oct 7, 2020
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40
The idea of irreversible inhibitors adhering permanently to a target protein has gained increasing attention for application in potential drug development. However, one of many hurdles is the possibility of protein mutations ...
Biochemistry
Nov 29, 2023
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20
Protein-based drugs are used in the treatment of every kind of malady, from cancer to heart disease to rheumatoid arthritis. But the proteins are almost always modified with chemical appendages that help them navigate through ...
Biochemistry
Nov 21, 2016
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11
Scientists have invented a new "synthetic antibody" that could make screening for diseases easier and less expensive than current go-to methods. Writing in the journal Nano Letters, a team led by Markita Landry of Berkeley ...
Bio & Medicine
Apr 30, 2019
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7
Molecular chaperones have emerged as exciting new potential drug targets, because scientists want to learn how to stop cancer cells, for example, from using chaperones to enable their uncontrolled growth. Now a team of biochemists ...
Biochemistry
Dec 6, 2012
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1
A Purdue University researcher ranks among the best in the world in bioinformatics competitions to predict protein structure, docking and function, making him a triple threat in the world of protein modeling.
Cell & Microbiology
Mar 30, 2015
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8
University of Adelaide research has produced a potential new antibiotic which could help in the battle against bacterial resistance to antibiotics.
Biochemistry
Jul 3, 2013
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0
New research shows a physical characterisation of the interface of the body's proteins with water. Identifying the locations where it is easiest to remove water from the interface of target proteins could constitute a novel ...
Materials Science
Jul 30, 2013
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0
Recent advances in imaging technology have made it possible to visualize intracellular dynamics, which offers a better understanding of several key biological principles for accelerating therapeutic development. Fluorescent ...
Biochemistry
Sep 8, 2022
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89
When agricultural weeds evolve resistance to herbicides, they do it in one of two ways. In target-site resistance, a tiny mutation in the plant's genetic code means the chemical no longer fits in the protein it's designed ...
Plants & Animals
Aug 16, 2021
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11
