A mutated protein causes the genetic disease cystic fibrosis. Now, researchers have solved the structure of the protein and how certain drugs bind to it, unveiling their mode of action.
Cell & Microbiology
Jan 7, 2022
0
590
Scientists at ETH Zurich have developed a new method to determine how proteins are organized on the surface of cells. Insights gained with the technology could lead to the development of novel drugs to fight cancer.
Cell & Microbiology
Dec 2, 2021
0
112
Centrioles are cylindrical structures involved in the generation of microtubules—fibers inside of cells that form a network to provide structure and shape to cells and to mediate transport processes. In addition, centriole ...
Molecular & Computational biology
Nov 1, 2021
0
54
Some proteins in cells can separate into small droplets like oil droplets in water, but faults in this process may underlie neurodegenerative diseases in the brains of older people. Now, Rutgers researchers have developed ...
Soft Matter
Aug 13, 2021
0
434
For decades, scientists suspected that bacteria known as Geobacter could clean up radioactive uranium waste, but it wasn't clear how the microbes did it.
Cell & Microbiology
Aug 12, 2021
0
388
Nanoengineers at the University of California San Diego have developed immune cell-mimicking nanoparticles that target inflammation in the lungs and deliver drugs directly where they're needed. As a proof of concept, the ...
Bio & Medicine
Jun 16, 2021
0
1306
A new, detailed model of the surface of the SARS-CoV-2 spike protein reveals previously unknown vulnerabilities that could inform development of vaccines. Mateusz Sikora of the Max Planck Institute of Biophysics in Frankfurt, ...
Molecular & Computational biology
Apr 1, 2021
0
253
Scientists at the Institute for Integrated Cell-Material Sciences (iCeMS) and colleagues in Japan have revealed molecular mechanisms involved in eliminating unwanted cells in the body. A nuclear protein fragment released ...
Cell & Microbiology
Mar 26, 2021
2
955
A team of scientists led by Dietmar Krautwurst from the Leibniz Institute for Food Systems Biology at the Technical University of Munich has now identified address codes in odorant receptor proteins for the first time. Similar ...
Cell & Microbiology
Mar 17, 2021
0
7
Plants perceive pathogens and activate immunity using two very different types of receptors. Receptors at the cell surface detect pathogen-derived molecules that accumulate outside plant cells, activating pattern-triggered ...
Plants & Animals
Mar 11, 2021
0
120
