Examining a nanocrystal that shines on and off indefinitely

In 2021, lanthanide-doped nanoparticles made waves—or rather, an avalanche—when Changwan Lee, then a Ph.D. student in Jim Schuck's lab at Columbia Engineering, set off an extreme light-producing chain reaction from ultrasmall ...

AIM algorithm enhances super-resolution microscope images in real time

When trying to measure molecular structures with nanometer precision, every bit of noise shows up in the data: someone walking past the microscope, tiny vibrations in the building and even the traffic outside. A new processing ...

Advanced microscopy technique offers a new look inside cells

Imagine tuning into a football game, but all of the players are invisible except for the two quarterbacks. Without being able to see the orchestrated movements of the full teams, this would be a very confusing game to watch.

Scientists identify novel lysosome fission factor

Lysosomes are centers for degradation, recycling, and signaling of cellular materials that are crucial for maintaining cellular homeostasis, development, and aging. To meet various physiological demands, lysosomes continuously ...

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