RIKEN researchers have developed a promising method to deliver a drug to cancer cells without affecting surrounding tissues, involving a clever combination of an artificial metalloenzyme that protects a metal catalyst, and ...
Materials Science
Jul 1, 2019
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2
It has long been known that the pathogens causing sleeping sickness evade the immune system by exchanging their surface proteins. But now scientists at the German Cancer Research Center (DKFZ) have found an additional parasite ...
Cell & Microbiology
Jul 10, 2018
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94
ETH researchers have succeeded in determining the 3-D structure of the enzyme that attaches sugar chains to proteins – a breakthrough that they recently published in the journal Science.
Biochemistry
Feb 8, 2018
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33
Bacteria are particularly ingenious when it comes to survival strategies. They often create a biofilm to protect themselves from a hostile environment, for example during treatment with antibiotics. A biofilm is a bacterial ...
Cell & Microbiology
Sep 14, 2014
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0
A team of investigators from the University of Georgia recently demonstrated the first method for synthesizing asymmetrical N-glycans. According to the study, published in the journal Science on July 25, the approach could ...
Cell & Microbiology
Aug 8, 2013
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0
Scientists from Germany today reported a major advance toward opening the doors of a carbohydrate-based medicine chest for the 21st Century. Much more than just potatoes and pasta, these carbohydrates may form the basis ...
Biochemistry
Mar 22, 2009
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0
Every organism has an associated glycome, a unique profile of associated carbohydrates also known as sugar chains or glycans. Glycomics, the study of individual glycomes, may lead to the development of new strategies for ...
Molecular & Computational biology
Jun 20, 2023
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3
Protein nanopores are present in cell membranes and act as biological gateways. This means that they can also be used for the detection of specific bioactive molecular chains, like sugar chains, such as molecules from the ...
Nanomaterials
Nov 8, 2018
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8
Sugar structures called GAGs are present in almost all tissues in the human body, and have important functions in various diseases. The understanding of these sugar structures is limited, because tools to study them have ...
Biochemistry
Aug 15, 2018
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9
A team led by researchers at the RIKEN Biofunctional Synthetic Chemistry Laboratory in Japan has developed a way to engineer glycan complexes—clusters of sugar chains attached to proteins or lipids—in a way that allows ...
Biochemistry
Nov 28, 2016
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5
