Just like people, cells get stressed too. A sudden drop in oxygen, overheating, or toxins can trigger a cascade of molecular changes that lead cells to stop growing, produce stress-protective factors, and form stress granules—proteins ...
Cell & Microbiology
Dec 14, 2020
0
19
Cells require a balance among oxidation-reduction reactions, or redox homeostasis. Loss of that balance to create oxidative stress is often associated with neurodegeneration. Less is known about how loss of that balance at ...
Cell & Microbiology
Dec 9, 2020
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2
Of all the exciting topics in the field of material and biochemical research, one of the hottest by far is unraveling the mysteries of spider silk.
Materials Science
Nov 30, 2020
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23
Environmental extremes driven by climate change create stresses in crops, and plant breeders are attempting to untangle the genetic factors that endow plants with tolerance to stress. A new study from Iowa State University ...
Plants & Animals
Aug 27, 2020
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28
When cells experience a high level of stress—for example, when they are exposed to too much UV light—ribosomes inside the cell collide and get into traffic jams. Now, Johns Hopkins scientists have found a protein that ...
Cell & Microbiology
Aug 5, 2020
0
128
Heat shock protein 70 (Hsp70) proteins are a family of ancient and conserved molecular chaperones. They play an essential role in maintaining protein homeostasis, including facilitating protein folding and degradation, preventing ...
Biochemistry
Jul 27, 2020
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10
There is a broad range of mechanisms associated with chemoresistance, many of which to date are only poorly understood. The so-called cellular stress response—a set of genetic programs that enable the cells to survive under ...
Cell & Microbiology
Jun 10, 2020
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141
The conditions in the environment are subject to large fluctuations. In Germany, for instance, temperatures can range from a freezing minus 20 degrees Celsius in the winter to a hot 40 degrees Celsius in the summer. Organisms ...
Evolution
May 11, 2020
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6
St. Jude Children's Research Hospital investigators are studying the details of how phase separation leads to the formation of RNA granules, assemblies of protein and RNA that are not bound by a membrane. Their findings show ...
Cell & Microbiology
Apr 17, 2020
0
133
Networks are at the heart of everything from communications systems to pandemics. Now researchers have found that a unique type of network also underlies the structures of critical cellular compartments known as membraneless ...
Cell & Microbiology
Apr 16, 2020
0
56
