A unique approach for studying changes in chemical markers on DNA

A new method to study specific changes in DNA after replication has been published as a technical report in Nature Cell Biology. Researchers developed a highly sensitive, quantitative mass spectrometry-based approach, called ...

DNA repair scheme gets closer look for cancer therapy

Researchers from Rice University and St. Jude Children's Research Hospital in Memphis, Tennessee, Have taken a close look at one of the ways cells repair broken strands of DNA and discovered details that could help make a ...

CRISPR insight: How to fine-tune Cas protein's grip on DNA

At the heart of every CRISPR reaction, whether naturally occurring in bacteria or harnessed by CRIPSR-Cas gene editing technology, is a strong molecular bond of a Cas protein via a guide RNA to its target site on DNA. It's ...

Even good gene edits can go bad

A Rice University lab is leading the effort to reveal potential threats to the efficacy and safety of therapies based on CRISPR-Cas9, the Nobel Prize-winning gene editing technique, even when it appears to be working as planned.

The cell sentinel that neutralizes hepatitis B

The hepatitis B virus (HBV) is responsible for one of the most serious and common infectious diseases. Transmitted through biological fluids, it attacks the liver cells. The chronic form of the disease can lead to serious ...

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