Researchers develop method for DNA programmed material synthesis

For the first time, engineers of Friedrich-Alexander Universität Erlangen Nürnberg (FAU) have succeeded in producing complex crystal lattices, so-called clathrates, from nanoparticles using DNA strands. The programmed synthesis ...

Anticancer mechanism revealed in yeast experiments

Much like shoelaces or dangly necklaces, DNA strands can tangle up in unruly knots. Specialized enzymes keep DNA organized when cells divide, so the cells split smoothly and don't get stuck. But in tumor cells, this failsafe ...

DNA design brings predictability to polymer gels

Scientists in Japan have made a tuneable, elastic and temperature-sensitive gel by using complementary DNA strands to connect star-shaped polymer molecules together. The gel, and the method used to develop it, could lead ...

Researchers identify the source of asymmetry in RNA-DNA hybrids

A study headed by the Institute for Research in Biomedicine (IRB Barcelona) and published in the journal CHEM furthers the understanding of the asymmetry between nucleic acid hybrids. This advance may make a significant contribution ...

Locating and severing lethal links in DNA

Chemical lesions in the genetic material DNA can have catastrophic consequences for cells, and even for the organism concerned. This explains why the efficient identification and rapid repair of DNA damage is vital for survival. ...

A protein with a dual role: Both repair and mutation

Using a specialized protein, all bacteria are capable of rapidly and effectively repairing damage to their DNA from UV. However, this mutation frequency decline (Mfd) protein plays another role and causes mutations. A team1 ...

CRISPR insight: How to fine-tune Cas protein's grip on DNA

At the heart of every CRISPR reaction, whether naturally occurring in bacteria or harnessed by CRIPSR-Cas gene editing technology, is a strong molecular bond of a Cas protein via a guide RNA to its target site on DNA. It's ...

Scientists use DNA origami to monitor CRISPR gene targeting

The remarkable genetic scissors called CRISPR/Cas9, the discovery that won the 2020 Nobel Prize in Chemistry, sometimes cut in places that they are not designed to target. Though CRISPR has completely changed the pace of ...

Bacteria pack their own demise

Numerous pathogens contain an 'internal time bomb', a deadly mechanism that can be used against them. After years of work, VIB researchers at the Vrije Universiteit Brussel (VUB) were able to determine the structure and operating ...

Analyzing gut bacteria more accurately to make diagnosis

The microorganisms in our intestines could be linked to certain diseases such as Alzheimer's and diabetes. Researchers from the AD-gut consortium have developed a novel method—combining optical DNA mapping and statistics—for ...

page 40 from 40