3-D culturing hepatocytes on a liver-on-a-chip device

Liver-on-a-chip cell culture devices are attractive biomimetic models in drug discovery, toxicology and tissue engineering research. To maintain specific liver cell functions on a chip in the lab, adequate cell types and ...

How stem cells self-organize in the developing embryo

Embryonic development is a process of profound physical transformation, one that has challenged researchers for centuries. How do genes and molecules control forces and tissue stiffness to orchestrate the emergence of form ...

How trees and turnips grow fatter

Two international research teams have identified key regulatory networks controlling how plants grow 'outwards', which could help us to grow trees to be more efficient carbon sinks and increase vegetable crop yields.

Honeybee protein keeps stem cells youthful

An active protein component of royal jelly helps honeybees create new queens. Stanford researchers have identified a similar protein in mammals, which keeps cultured embryonic stem cells pluripotent.

When it comes to regrowing tails, neural stem cells are the key

Cut off a salamander's tail and, in a few weeks, a near-perfect replacement grows. Do the same to a lizard and a new tail will regrow, but it won't be the same as the original. By comparing tail regeneration between the two ...

A 3-D model of a human heart ventricle

Harvard University researchers have bioengineered a three-dimensional model of a human left heart ventricle that could be used to study diseases, test drugs and develop patient-specific treatments for heart conditions such ...

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