The ability to reprogram adult cells so they return to an undifferentiated, pluripotent state—much like an embryonic stem cell—is enabling the development of promising new cell therapies. Accelerating progress in this ...
Cell & Microbiology
Feb 6, 2014
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One major challenge in stem cell research has been to reprogram differentiated cells to a totipotent state. Researchers from RIKEN in Japan have identified a duo of histone proteins that dramatically enhance the generation ...
Cell & Microbiology
Feb 6, 2014
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A fundamental axiom of biology used to be that cell fate is a one-way street—once a cell commits to becoming muscle, skin, or blood it always remains muscle, skin, or blood cell. That belief was upended in the past decade ...
Cell & Microbiology
Jan 30, 2014
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Embryonic stem cells (ESCs) retain their ability to self-renew indefinitely thanks to a number of proteins known as pluripotency factors. These factors must be modified at the RNA level before they are turned into proteins ...
Cell & Microbiology
Jan 29, 2014
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(Phys.org) —Since the discovery of human embryonic stem cells, scientists have had high hopes for their use in treating a wider variety of diseases because they are pluripotent, which means they are capable of differentiating ...
Cell & Microbiology
Jan 29, 2014
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Scientists from the Genome Institute of Singapore (GIS) in A*STAR have developed a novel method of directing human pluripotent stem cells (hPSCs) into highly pure populations of endoderm, a valuable cell type that gives rise ...
Cell & Microbiology
Jan 28, 2014
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Scientists at Karolinska Institutet and Gurdon Institute in Cambridge, United Kingdom have identified a novel mechanism that allows pluripotent stem cells to maintain their genome in an unpacked state, and thereby maintain ...
Cell & Microbiology
Jan 27, 2014
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A new method allows for large-scale generation of human embryonic stem cells of high clinical quality. It also allows for production of such cells without destroying any human embryos. The discovery is a big step forward ...
Cell & Microbiology
Jan 27, 2014
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The Wnt/β-catenin signaling pathway and microRNA 335 are instrumental in helping form differentiated progenitor cells from stem cells. These are organized in germ layers and are thus the origin of different tissue types, ...
Cell & Microbiology
Jan 23, 2014
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In an early indication of lay opinions on research with induced pluripotent stem cells (iPSCs), which are stem cells made from skin or other tissues, a new study by bioethicists at Johns Hopkins University indicates that ...
Cell & Microbiology
Jan 2, 2014
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