How human eggs end up with the wrong number of chromosomes

One day before ovulation, human oocytes begin to divide into what will become mature eggs. Ideally, eggs are packaged with a complete set of 23 chromosomes, but the process is prone to error, especially with age. In a Review ...

A missing 'motor' causes human eggs to fail

Human eggs often contain the wrong number of chromosomes, leading to miscarriages and infertility. A research team led by Melina Schuh at the Max Planck Institute (MPI) for Multidisciplinary Sciences has discovered that human ...

Decoding cell division's mysterious spindle matrix

Every high school biology class learns about the tiny cells that comprise our bodies, as well as about many of the diverse actions that they perform. One of these actions is called mitosis, the series of steps through which ...