Somatic cell nuclear transfer (SCNT, also known as cloning) technology holds great potential in animal production and regenerative medicine. However, the extremely low efficiency and frequently observed abnormalities in cloned ...
Biotechnology
Jun 19, 2020
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6
The many types of cells in the human body are produced through the process of differentiation, in which stem cells are converted to more specialized types. Currently, it is challenging for researchers to control the differentiation ...
Cell & Microbiology
May 25, 2023
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41
Induced pluripotent stem cells offer great therapeutic potential and are a valuable tool for understanding how different diseases develop. New research shows that such stem cell lines should be regularly screened for genetic ...
Cell & Microbiology
Mar 24, 2023
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30
A team led by Chris Sullivan, a professor of molecular biosciences at The University of Texas at Austin, has provided the first positive evidence that RNA interference (RNAi), a biological process in which small RNA molecules ...
Cell & Microbiology
Oct 15, 2013
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0
Not unlike looking for the proverbial needle in a haystack, a team of Michigan State University researchers have found a gene that could be key to the development of stem cells – cells that can potentially save millions ...
Cell & Microbiology
Jul 17, 2014
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A research team led by the group of Professor Yasuhiro Yamada, Center for iPS Cell Research and Application (CiRA), Kyoto University, has discovered that when cells are subjected to incomplete reprogramming in vivo, epigenetic ...
Cell & Microbiology
Mar 14, 2014
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1
An international team of seven institutions from Spain and the US including the University of Valencia has discovered for the first time that the biological activity of the c-MYC gene is necessary for cell reprogramming, ...
Cell & Microbiology
Nov 30, 2018
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8
Researchers in China are reporting that they have found a way to determine which somatic cells -- or differentiated body cells -- that have been reprogrammed into a primordial, embryonic-like state are the most viable for ...
Biochemistry
Apr 16, 2010
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0
While it is known that stem cells have the ability to develop into all tissues in a precisely regulated process, the way environmental cues affect stem cell behavior has remained poorly understood. In a new study, researchers ...
Cell & Microbiology
Oct 20, 2020
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57
University of Tsukuba-led researchers explored the function of the reprogramming factor KLF4 in production of induced pluripotent stem cells (iPSCs). KLF4 was shown to bind upstream of the Tcl1 target gene, which controls ...
Cell & Microbiology
Mar 8, 2017
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