Reconstructing the life history of a single cell

Researchers have developed new methods to trace the life history of individual cells back to their origins in the fertilised egg. By looking at the copy of the human genome present in healthy cells, they were able to build ...

Carcinogenic mechanism of incomplete cell reprogramming in vivo

A research team led by the group of Professor Yasuhiro Yamada, Center for iPS Cell Research and Application (CiRA), Kyoto University, has discovered that when cells are subjected to incomplete reprogramming in vivo, epigenetic ...

Fly dreams and the boundaries of evolutionary science

In 2002, Secretary of state Donald Rumsfeld made a statement regarding weapons of mass destruction that today is still well known. He famously parsed the evidence (or lack thereof) into "known knowns, known unknowns, and ...

Aging human bodies and aging human oocytes run on different clocks

Reproductive and somatic aging use different molecular mechanisms that show little overlap between the types of genes required to keep oocytes healthy and the genes that generally extend life span, according to Coleen Murphy, ...

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