30,000-year-old virus from permafrost is reborn
French scientists said Monday they had revived a giant but harmless virus that had been locked in the Siberian permafrost for more than 30,000 years.
French scientists said Monday they had revived a giant but harmless virus that had been locked in the Siberian permafrost for more than 30,000 years.
Biotechnology
Mar 3, 2014
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Medical researchers have unlocked the human genome, wiped out smallpox and made great strides in the fight against AIDS.
Other
Jun 7, 2011
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A team of researchers working in a high containment laboratory at the Centers for Disease Control and Prevention in Atlanta, GA, have solved a fundamental mystery about smallpox that has puzzled scientists long after the ...
Cell & Microbiology
Dec 22, 2009
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In an ongoing effort to mirror the ability of biological tissues to respond rapidly and appropriately to changing environments, scientists from the McGowan Institute for Regenerative Medicine have synthesized a single, multifunctional ...
Polymers
Mar 18, 2010
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When University of Kansas researcher Paul Kelton came across a description from missionary Daniel Butrick that documented a Cherokee ritual aimed at fighting smallpox, it revolutionized Kelton's thinking about the role diseases ...
Other
Apr 21, 2015
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ETH Zurich researchers demonstrate how vaccinia virus manipulates the cellular waste-disposal system and thereby cleverly tricks the cell into assisting the intruders replication. Now, the virologists have turned the tables, ...
Cell & Microbiology
Oct 19, 2012
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A new study by Anna Maria Niewiadomska and Robert Gifford, of The Aaron Diamond AIDS Research Center, New York, reveals that reticuloendotheliosis viruses (REVs), which originated in mammals, spread to birds as a result of ...
Cell & Microbiology
Aug 27, 2013
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Australia was first settled by between 1,000 and 3,000 humans around 50,000 years ago, but the population crashed during the Ice Age before recovering to a peak of some 1.2 million people around five centuries ago, a study ...
Archaeology
Apr 23, 2013
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In a laboratory in Alberta, Canada, a team of scientists recently pieced together overlapping segments of mail order DNA to form a synthetic version of an extinct virus.
Biotechnology
Jul 11, 2017
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Smallpox was once one of humanity's most devastating diseases, but its origin is shrouded in mystery. For years, scientific estimates of when the smallpox virus first emerged have been at odds with historical records. Now, ...
Evolution
Jan 9, 2023
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Smallpox is an infectious disease unique to humans, caused by either of two virus variants, Variola major and Variola minor. The disease is also known by the Latin names Variola or Variola vera, which is a derivative of the Latin varius, meaning spotted, or varus, meaning "pimple". The term "smallpox" was first used in Europe in the 15th century to distinguish variola from the "great pox" (syphilis).
Smallpox localizes in small blood vessels of the skin and in the mouth and throat. In the skin, this results in a characteristic maculopapular rash, and later, raised fluid-filled blisters. V. major produces a more serious disease and has an overall mortality rate of 30–35%. V. minor causes a milder form of disease (also known as alastrim, cottonpox, milkpox, whitepox, and Cuban itch) which kills about 1% of its victims. Long-term complications of V. major infection include characteristic scars, commonly on the face, which occur in 65–85% of survivors. Blindness resulting from corneal ulceration and scarring, and limb deformities due to arthritis and osteomyelitis are less common complications, seen in about 2–5% of cases.
Smallpox is believed to have emerged in human populations about 10,000 BC. The disease killed an estimated 400,000 Europeans each year during the 18th century (including five monarchs), and was responsible for a third of all blindness. Of all those infected, 20–60%—and over 80% of infected children—died from the disease.
During the 20th century, it is estimated that smallpox was responsible for 300–500 million deaths. In the early 1950s an estimated 50 million cases of smallpox occurred in the world each year. As recently as 1967, the World Health Organization estimated that 15 million people contracted the disease and that two million died in that year. After successful vaccination campaigns throughout the 19th and 20th centuries, the WHO certified the eradication of smallpox in December 1979. To this day, smallpox is the only human infectious disease to have been completely eradicated.
This text uses material from Wikipedia, licensed under CC BY-SA