How to find molecular glues to effectively target diseases

Many of the currently available drugs are not specific enough to effectively cure complex diseases such as cancer, neurodegenerative diseases and diabetes. In addition, drug resistance reduces the effectiveness of existing ...

Faster modeling of interactions between ligands and proteins

A computational method for simulating the interaction between small molecules and proteins has been enhanced by an all-RIKEN team. This improvement promises to boost the speed and accuracy of designing new drugs.

Building a better battery with machine learning

Designing the best molecular building blocks for battery components is like trying to create a recipe for a new kind of cake, when you have billions of potential ingredients. The challenge involves determining which ingredients ...

Stabilizing ligands make nanoclusters brighter

Metal nanoclusters that bear tunable surface ligands could help develop next-generation imaging and photocatalytic approaches, suggests work by KAUST researchers.

Antibiotics from the sea

The team led by Prof. Christian Jogler of Friedrich Schiller University, Jena, has succeeded in cultivating several dozen marine bacteria in the laboratory—bacteria that had previously been paid little attention. The researchers ...

New polymer releases molecular cargo in response to force

Caltech scientists have developed a new kind of polymer that can carry a chemical payload as part of its molecular structure and release it in response to mechanical stress. The chemical system they have developed could one ...

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