Scientists working in a range of disciplines joined forces to identify a new approach to combat African sleeping sickness. Fundamental research undertaken under the supervision of Professor Ute Hellmich of Johannes Gutenberg ...
Biochemistry
Feb 21, 2019
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7
Trypanosoma brucei, which causes sleeping sickness, evades the immune system by repeatedly altering the structure of its surface coat. Sequencing of its genome and studies of its 3-D genome architecture have now revealed ...
Cell & Microbiology
Oct 18, 2018
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36
Sleeping sickness-causing parasites contain an unusual protein synthesis mechanism. A team of researchers from ETH Zurich and the University of Bern have resolved its very special structure for the first time. Ribosomes are ...
Cell & Microbiology
Sep 14, 2018
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64
Researchers at the University of Dundee have identified a new drug target in parasites that cause major neglected tropical diseases, a discovery that contributes towards a global drive to eliminate these diseases by 2030.
Cell & Microbiology
Sep 4, 2018
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7
Trypanosomes are single-celled parasites that cause diseases such as human African sleeping sickness and Nagana in animals. But they are also used in basic research as a model system to study fundamental biological questions. ...
Cell & Microbiology
Feb 22, 2018
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4
Yaser Hashem's team at the Laboratoire Architecture et Réactivité de l'ARN at CNRS's has discovered a new potential therapeutic target - located in the ribosome - to combat trypanosomes parasites. Using cryo-electron microscopy, ...
Cell & Microbiology
Oct 26, 2017
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2
New insight into sleeping sickness suggests communication between parasites that cause infection could affect the severity and spread of the disease.
Cell & Microbiology
Sep 5, 2017
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62
Blood-sucking flies can act as 'flying syringes' to detect emerging infectious diseases in wild animals before they spread to humans, according to research published in the journal eLife.
Ecology
Mar 28, 2017
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28
A team of researchers from iMM Lisboa led by Luísa Figueiredo and in collaboration with Joe Takahashi's group from Southwestern University has shown for the first time that the parasite responsible for sleeping sickness, ...
Cell & Microbiology
Mar 13, 2017
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7
Researchers have made the first-ever detailed, atomic-level images of a peroxiredoxin, which has revealed a peculiar characteristic of this protein and might form the foundation for a new approach to antibiotics.
Biochemistry
Sep 1, 2016
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51
