Identifying different types of cells within a tissue or an organ can be very challenging and time-consuming. Methods to identify cell types from single-cell RNA sequencing data have been proposed, but they all fall short ...
Cell & Microbiology
May 19, 2020
0
37
Single-cell RNA sequencing (scRNA-seq) has revolutionized the ability to characterize cell types and their gene expression programs in organisms and tissues. Although great improvements in cellular throughput have been made, ...
Biotechnology
May 7, 2020
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37
A new computational method for assigning the donor in single cell RNA sequencing experiments provides an accurate way to unravel data from a mixture of people. The Souporcell method, created by Wellcome Sanger Institute researchers ...
Biotechnology
May 6, 2020
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127
A team led by researchers at the Max Planck Institute (MPI) for Marine Microbiology has developed, tested and deployed a pipeline to first target cells from communities of uncultivated microbes, and then efficiently retrieve ...
Cell & Microbiology
Apr 24, 2020
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75
Biologists have long hoped to understand the nature of the earliest living organisms on Earth. If they could, they might then be able to say something about how, when, and where life arose on Earth, and perhaps by extension, ...
Evolution
Apr 22, 2020
4
466
"How are the many different cell types in the body generated during embryonic development from an egg, which is only a single cell? This is one of the most fundamental questions in biology," explains Dr. Pierre Neveu, group ...
Cell & Microbiology
Apr 20, 2020
0
107
Researchers investigated the group of microorganisms classified as Asgard archaea, and found a protein in their membrane which acts as a miniature light-activated pump. The schizorhodopsin protein draws protons into the organisms' ...
Cell & Microbiology
Apr 10, 2020
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180
With the goal of ensuring that single-cell RNA sequencing makes use of the best possible methods, an international group has benchmarked 13 methods. The group, led by Holger Heyn of the Centro Nacional de Análisis Genómico ...
Biotechnology
Apr 6, 2020
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24
A large team of researchers affiliated with multiple institutions in and around Hangzhou, China, has taken a very large step toward the creation of a comprehensive human single-cell atlas. In their paper published in the ...
Microbiologists have long adopted the language of human settlement to describe how bacteria live and grow: They "invade" and "colonize." Relations dwelling in close proximity are "colonies."
Cell & Microbiology
Mar 13, 2020
0
457
