Cross-species cell landscape constructed at single-cell level

Thanks to high-throughput single-cell RNA sequencing (scRNA-seq), it is possible to construct single-cell transcriptomic atlases at the organic level. For example, cell atlases for vertebrate and invertebrate systems have ...

Artificial cells produce parts of viruses for safe studies

Scientists searching for better diagnostic tests, drugs or vaccines against a virus must all begin by deciphering the structure of that virus. And when the virus in question is highly pathogenic, investigating, testing or ...

Making heads or tails out of phospholipid synthesis

Most scientists agree that life on Earth began about 4 billion years ago, but they don't agree where—on land or in water. They know that about 2 billion years ago, single-celled organisms evolved into complex plants and ...

The unexpected relatives of smallpox

(PhysOrg.com) -- A protein shared by the simple viruses that infect single-cell organisms, and their highly complex counterparts that affect mammals, could hold to the key to understanding and ultimately neutralising the ...

E. Coli calculus: Bacteria find the derivative optimally

Scientists from the Graduate School of Information Science and Technology at The University of Tokyo calculated the efficiency of the sensory network that bacteria use to move towards food and found it to be optimal from ...

New function for potential tumor suppressor in brain development

The gene Cdkn1c could have been considered an open-and-shut case: Mice in which the gene is removed are larger and have bigger brains, so Cdkn1c should function to inhibit growth. This rationale has led to Cdkn1c being studied ...

Single-cell genome sequencing gets better (w/ Video)

(Phys.org) —Bioengineers at the Jacobs School have created a better way to sequence genomes from individual cells. The breakthrough, which relies on microwells just 12 nanoliters in volume (see image), is one of many recent ...

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