DNA accessibility, gene expression jointly profiled in thousands of cells
Scientists have now developed an assay that concurrently profiles both the epigenome and transcriptome of each of thousands of single cells.
Scientists have now developed an assay that concurrently profiles both the epigenome and transcriptome of each of thousands of single cells.
Cell & Microbiology
Aug 30, 2018
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71
One of the big evolutionary questions in life is how and why single cell organisms organised themselves to live in a group, thereby forming multicellular life forms.
Evolution
Feb 2, 2018
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329
An interdisciplinary team of researchers at the University of California San Diego has developed a technology for very accurate sequencing and haplotyping of genomes from single human cells. Their findings were published ...
Biotechnology
Nov 2, 2017
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126
I've often wondered what happens between the time an egg is fertilized and the time the ball of cells that it becomes nestles into the uterine lining. It's a period that we know very little about, a black box of developmental ...
Medical research
May 27, 2016
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6
The Krüppel-like factor and specificity protein (KLF/SP) genes are found across many species, ranging from single cell organisms to humans. This gene family has been conserved during evolution, because it plays a vital role ...
Evolution
Aug 18, 2015
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Some wild microorganisms, found in nature and not grown in the laboratory, reinterpret the instructions coded into their DNA. Short segments of DNA that signal other organisms to stop adding building blocks or amino acids ...
Cell & Microbiology
Apr 13, 2015
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(Phys.org) —Bioengineers at the Jacobs School have created a better way to sequence genomes from individual cells. The breakthrough, which relies on microwells just 12 nanoliters in volume (see image), is one of many recent ...
Biotechnology
Jan 16, 2014
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In 2011, Nature announced that scientists had discovered a single-celled organism that is a primitive farmer. The organism, a social amoeba called Dictyostelium discoideum, picks up edible bacteria, carries them to new locations ...
Biotechnology
Jul 29, 2013
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(PhysOrg.com) -- In the long evolutionary road from bacteria to humans, a major milestone occurred some 1.5 billion years ago when microbes started building closets for all their stuff, storing DNA inside a nucleus, for example, ...
Cell & Microbiology
Mar 4, 2010
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