Mini but mighty: Tiny WNT messengers help muscles grow

WNT signaling is crucial for the development of organisms and the maintenance of tissue homeostasis, since the WNT messengers are involved in a variety of cellular functions. In skeletal muscle, for example, they can increase ...

Mitochondrial unfolded protein response signals imminent danger

Misfolded proteins must be promptly eliminated as they can form toxic aggregates in cells. LMU biologists have studied how this process is triggered in mitochondria and identified a general alarm signal that activates it.

How plants can tell time even without a brain

Anyone who has traveled across multiple time zones and suffered jet lag will understand just how powerful our biological clocks are. In fact, every cell in the human body has its own molecular clock, which is capable of generating ...

Using a promiscuous inhibitor to uncover cancer drug targets

Scientists at Harvard Medical School and the Dana-Farber Cancer Institute have developed a method that exploits the multitargeted nature of a chemical inhibitor to pinpoint vulnerabilities within cancer cells.

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