G protein-coupled receptors (GPCRs) are the largest class of cell surface receptors in our cells, involved in signal transmission across the cell membrane. One of the biggest questions is how a signal recognized at the extracellular ...
Cell & Microbiology
Sep 9, 2014
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1
Researchers from Hull, Bristol and Frankfurt have shown that a new technique for identifying molecular structure can be used effectively on small samples of biological proteins, particularly proteins that are targeted for ...
Biochemistry
Nov 14, 2011
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0
The Notch signaling pathway helps determine cell fate determination, differentiation and proliferative ability of numerous cells. How it accomplishes these tasks has been a puzzle, but researchers led by those at Baylor College ...
Cell & Microbiology
Nov 29, 2012
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0
Researchers at Stockholm University have unveiled the hidden intricacies of how sperm go from passive bystanders to dynamic swimmers. This transformation is a pivotal step in the journey to fertilization, and it hinges on ...
Cell & Microbiology
Oct 25, 2023
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1
During the process of cellular protein synthesis mistakes can happen. Sometimes, proteins end up being misfolded. They do not shape up into the specific 3-D structure that is required for proper function. Misshaped secreted ...
Cell & Microbiology
Aug 25, 2020
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7
When exposed to stress, bacteria allow their metabolism to take a break during which they suppress, for example, the incorporation of proteins into membranes. Scientists from Marburg, Freiburg and Munich have discovered this ...
Cell & Microbiology
Mar 7, 2022
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73
Sections of proteins previously thought to be disordered may in fact have an unexpected biological role - providing certain proteins room to move -- according to a study published by researchers at Fox Chase Cancer Center ...
Cell & Microbiology
May 26, 2009
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0
Several bacterial pathogens use toxins to manipulate human host cells, ultimately disturbing cellular signal transduction. Until now, however, scientists have been able to track down only a few of the proteins that interact ...
Cell & Microbiology
Apr 22, 2009
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0
A new study reveals the importance of adenylylation in the regulation of cell signaling from bacteria to higher organisms. The research, published by Cell Press in the April 10th issue of the journal Molecular Cell, provides ...
Cell & Microbiology
Apr 9, 2009
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0
Scientists from MIPT, in collaboration with international colleagues, have proposed a universal mechanism for the sense of smell in bacteria. The researchers obtained the structure of the NarQ protein from Escherichia coli ...
Cell & Microbiology
May 22, 2017
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