Making CRISPR hype more of a reality

This year, we celebrate 10 years of genome editing with CRISPR. The system is often referred to as molecular scissors, and this designation is quite accurate for its first applications. These short 10 years were marked by ...

'Molecular scissors' could point the way to genetic cures

Guan-En Graham is determined to find out exactly what happened to her father. When she was a child, he developed brain cancer. Since then, she has worked to understand the intricate genetic mechanisms that trigger brain diseases ...

Scientists use light to uncover the cause of sickle cell disease

In sickle cell disease, hemoglobin—the oxygen-carrying component of blood—forms fibers that stiffen red blood cells and cause life-threatening symptoms. Using light-scattering techniques to study the detailed thermodynamics ...