Psychedelic drugs such as LSD, psilocybin, and mescaline cause severe and often long-lasting hallucinations, but they show great potential in treating serious psychiatric conditions, such as major depressive disorder. To ...
Cell & Microbiology
Sep 17, 2020
1
558
Psychedelic drugs have shown promise for treating neuropsychiatric disorders such as depression and posttraumatic stress disorder. However, due to their hallucinatory side effects, some researchers are trying to identify ...
Biochemistry
Apr 28, 2021
3
144
In November 2017, a Titan Krios cryo-electron microscope (cryo-EM) was inaugurated at the ESRF, the European Synchrotron, France. Data collected on this cryo-EM features in a Nature publication describing the activation cycle ...
Biochemistry
Oct 31, 2018
0
22
Serotonin, known as the "happiness" neurotransmitter, is a chemical found in the body responsible for feelings of well-being. But serotonin isn't the only chemical that binds to the 13 serotonin receptors found on the surface ...
Biochemistry
Aug 20, 2018
0
333
A team of researchers from Case Western Reserve University School of Medicine have used Nobel prize-winning microscope technology to see full length serotonin receptors for the first time. The tiny proteins—approximately ...
Biochemistry
Feb 6, 2018
0
57
One way or another, many psychiatric drugs work by binding to receptor molecules in the brain that are sensitive to the neurotransmitter dopamine, a chemical signal that is central to how our experiences shape our behavior. ...
Biochemistry
Oct 19, 2017
0
27
A tiny tab of acid on the tongue. A daylong trip through hallucinations and assorted other psychedelic experiences For the first time, researchers at the UNC School of Medicine have discovered precisely what the drug lysergic ...
Biochemistry
Jan 26, 2017
6
2865
EPFL scientists have elucidated for the first time how a notoriously elusive serotonin receptor functions with atom-level detail. The receptor transmits electrical signals in neurons and is involved in various disorders, ...
Biochemistry
Apr 21, 2016
0
42
An international research team has decoded the molecular structure of the medically important serotonin receptor at room temperature for the first time. This study reveals the dynamics of the receptor at close to its operating ...
General Physics
Dec 19, 2013
0
0
Using a novel optogenetic tool, researchers have successfully controlled, reproduced and visualised serotonin receptor signals in neural cells. To this end, they modified a photosensitive membrane receptor in the eye, namely ...
Biochemistry
Feb 14, 2019
0
5
