What makes one Argonaute a slicer and another one not? Human Argonaute proteins are key players in the gene regulation process known as RNA interference, RNAi. Professor Joshua-Tor's group of Cold Spring Harbor Laboratory ...
Cell & Microbiology
Jun 6, 2013
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The team of Johannes Zuber at the IMP in Vienna, Austria, managed to overcome remaining key limitations of RNA interference (RNAi) - a unique method to specifically shut off genes. By using an optimized design, the scientists ...
Cell & Microbiology
Dec 13, 2013
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RNAi-based biocontrol is a great alternative to hazardous pesticides and can contribute towards reversing the alarming decline in farmland birds and beneficial insects (especially pollinating ones).
Plants & Animals
Jan 27, 2021
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Researchers on the Broad Institute's Cancer Dependency Map (DepMap) team have released DEMETER2, an upgraded version of an open source software tool that identifies cancer cells' genetic dependencies (genes they need in order ...
Biotechnology
Nov 6, 2018
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In most organisms, small bits of RNA play a key role in gene regulation by silencing gene expression. They do this by targeting and docking onto complementary sequences of gene transcripts (also RNA molecules), which stop ...
Plants & Animals
Jul 28, 2020
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127
Sex pheromones are vital in facilitating the chemical communication that underpins insect courtship and mating behavior. Among female American cockroaches (Periplaneta americana), two key volatile sex pheromone components, ...
Plants & Animals
Apr 5, 2024
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A team of researchers led by Rutgers' Samuel Gunderson has developed a novel gene silencing platform with very significant improvements over existing RNAi approaches. This may enable the development and discovery of a new ...
Feb 15, 2009
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Cells produce proteins like little factories. But if they make too much at the wrong times it can lead to diseases like cancer, so they control production with a process called RNA interference (RNAi). As of July 2021, several ...
Cell & Microbiology
May 31, 2022
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Viruses have numerous tricks for dodging the immune system. In the September 7, 2009 issue of the Journal of Cell Biology, Stagg et al. reveal a key detail in one of these stratagems, identifying a protein that enables cyto-megalovirus ...
Cell & Microbiology
Aug 31, 2009
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Until the 1992 advent of a tomato that could delay softening, the fruit was picked green to withstand shipping. The delayed-softening trait was an example of the gene-silencing technique RNA interference, RNAi, before the ...
Biotechnology
Mar 7, 2024
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