Screening for genes to improve protein production in yeast

By silencing genes, researchers have managed to increase protein production in yeast significantly. This method can lay the grounds for engineering better yeast production hosts for industries producing biopharmaceutical ...

A molecular toolkit for gene silencing

The team of Johannes Zuber at the IMP in Vienna, Austria, managed to overcome remaining key limitations of RNA interference (RNAi) - a unique method to specifically shut off genes. By using an optimized design, the scientists ...

A new gene silencing platform -- silence is golden

A team of researchers led by Rutgers' Samuel Gunderson has developed a novel gene silencing platform with very significant improvements over existing RNAi approaches. This may enable the development and discovery of a new ...

The amazing travels of small RNAs

In most organisms, small bits of RNA play a key role in gene regulation by silencing gene expression. They do this by targeting and docking onto complementary sequences of gene transcripts (also RNA molecules), which stop ...

Decoding how a protein on the move keeps cells healthy

Cells produce proteins like little factories. But if they make too much at the wrong times it can lead to diseases like cancer, so they control production with a process called RNA interference (RNAi). As of July 2021, several ...

Study reveals how a common virus eludes the immune system

Viruses have numerous tricks for dodging the immune system. In the September 7, 2009 issue of the Journal of Cell Biology, Stagg et al. reveal a key detail in one of these stratagems, identifying a protein that enables cyto-megalovirus ...

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