New discovery shows human cells can write RNA sequences into DNA

Cells contain machinery that duplicates DNA into a new set that goes into a newly formed cell. That same class of machines, called polymerases, also build RNA messages, which are like notes copied from the central DNA repository ...

Scientists answer how bacteria fight toxic flouride

Yale researchers have uncovered the molecular tricks used by bacteria to fight the effects of fluoride, which is commonly used in toothpaste and mouthwash to combat tooth decay.

Novel polymer delivers genetic medicine, allows tracking

Theresa M. Reineke, associate professor of chemistry in the College of Science, and colleagues in her lab at Virginia Tech and at the University of Cincinnati have developed a new molecule that can travel into cells, deliver ...

Decoding the structure of an RNA-based CRISPR system

Over the past several years, CRISPR-Cas9 has moved beyond the lab bench and into the public zeitgeist. This gene-editing tool CRISPR-Cas9 holds promise for correcting defects inside individual cells and potentially healing ...

Scientists identify key enzyme in microbial immune system

Imagine a war in which you are vastly outnumbered by an enemy that is utterly relentless - attacking you is all it does. The intro to another Terminator movie? No, just another day for microbes such as bacteria and archaea, ...

Researchers reveal largest catalog of gene activators

University of Toronto researchers have created a first-in-class functional catalog of proteins that activate gene expression, with implications for tailored therapy for cancer and other diseases that occur when wrong genes ...

Silence of the genes

The molecular architecture of a protein complex that helps determine the fate of human cells has been imaged for the first time by researchers with the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley ...

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