New CRISPR-Cas approach permits more precise DNA cleavage

A team led by investigators at Massachusetts General Hospital (MGH) has overcome a major constraint for cutting and editing DNA by CRISPR-Cas enzymes and other technologies. The recent innovation, which is published in Nature ...

Team develops automated platform for plasmid production

Plasmids have extensive use in basic and applied biology. These small, circular DNA molecules are used by scientists to introduce new genes into a target organism. Well known for their applications in the production of therapeutic ...

How bacteria 'self-vaccinate' against viral invaders

Like most organisms, bacteria are preyed upon by viruses—and their go-to approach to destroying the invaders is to simply chop them up. As soon as it sees a virus, a bacterium may employ a host of immune strategies to slice ...

Method to customize microbes for better biofuel production

Scientists at the US Department of Energy's Oak Ridge National Laboratory have demonstrated a method to insert genes into a variety of microorganisms that previously would not accept foreign DNA, with the goal of creating ...

Prevention of RNA virus replication

Researchers at Okayama University have successfully cleaved influenza viral RNA to prevent its replication using novel artificial RNA restriction enzymes in laboratory cell cultures. While further improvements are needed, ...

Identifying sloth species at a genetic level

Identifying species, separating out closely related species and managing each type on its own, is an important part of any animal management system. Some species, like the two types of two-toed sloth, are so close in appearance ...

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