Toggling the functions of a protein that regulates gene expression during cellular reprogramming ensures cell fate conversion, an A*STAR study has found.
Cell & Microbiology
Nov 16, 2018
0
7
Vincent Pasque from KU Leuven, Belgium, and Kathrin Plath from UCLA led an international study into how specialized cells are reprogrammed to induced pluripotent stem cells (iPS). The researchers discovered that female and ...
Cell & Microbiology
Apr 19, 2018
0
146
In the field of regenerative medicine, induced pluripotent stem cells have a lot of neat tricks up their sleeves. One of them may be teaching the immune system how to beat back cancer.
Cell & Microbiology
Feb 16, 2018
2
77
Some heritable but unstable genetic mutations that are passed from parent to affected offspring may not be easy to investigate using current human-induced pluripotent stem cell (hiPSC) modeling techniques, according to research ...
Cell & Microbiology
Mar 13, 2017
0
8
Houston Methodist researchers have identified an immune pathway that promotes the formation of a cell that can develop into new tissues and organs.
Medical research
Mar 9, 2017
0
5
Cell reprogramming does not happen exactly as we thought. In the pages of the journal Science, a team from the Spanish National Cancer Research Centre (CNIO) has shown that tissue damage is a relevant factor for cells to ...
Cell & Microbiology
Nov 24, 2016
0
35
The effectiveness of reprogramming cells into blood cells is thought to depend on the original cell type and reprogramming method. Researchers at CiRA show this assumption is actually the result of epigenetic effects, suggesting ...
Cell & Microbiology
Jul 28, 2016
0
2
When Tokyo-based Fujifilm Holdings Corp. set out to become a global leader in the emerging area of regenerative medicine, one of the key places it turned to was Madison.
Business
Feb 5, 2016
0
12
Damaged tissue, such as pancreas, heart, and neuronal tissue, which is regenerated to treat cardiovascular diseases, diabetes, or neurodegenerative diseases. This is one of the ambitious scenarios to which regenerative medicine ...
Cell & Microbiology
Aug 27, 2015
0
63
Scientists from A*STAR's Genome Institute of Singapore (GIS) have discovered metabolic rejuvenation factors in eggs. This critical finding furthers our understanding of how cellular metabolism changes during aging, and during ...
Cell & Microbiology
Aug 13, 2015
0
31
