New type of map connects the dots in cellular reprogramming
A new use of an old mathematical method analyzes a massive single-cell RNA sequencing experiment to explore how cells move from one state to another.
A new use of an old mathematical method analyzes a massive single-cell RNA sequencing experiment to explore how cells move from one state to another.
Cell & Microbiology
Feb 1, 2019
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57
Our bodies consist of many different kinds of cells, each with their own role. The Japanese scientist Shinya Yamanaka had made earlier the discovery, earning the Nobel Prize in 2012, that cells from adult skin can be converted ...
Cell & Microbiology
Jul 6, 2018
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292
Over a decade ago, Shinya Yamanaka and Kazutoshi Takahashi made a discovery that would revolutionize biomedical research and trigger the field of regenerative medicine. They learned how to reprogram human adult cells into ...
Cell & Microbiology
Apr 10, 2018
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121
A new study has revealed an undiscovered reprogramming mechanism that allows plants to maintain fitness down the generations.
Biotechnology
Dec 18, 2017
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152
A series of studies led by Monash University researcher Associate Professor Jose Polo have this week shed light on vital, yet previously unclear, aspects of cell reprogramming.
Cell & Microbiology
Dec 7, 2017
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57
Researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have published a study demonstrating how specialized proteins are able to change the identity, or cellular characteristics, ...
Cell & Microbiology
Jan 20, 2017
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39
Researchers at ETH Zurich have managed to use a synthetic genetic program to instruct stem cells taken from fatty tissue to become cells that are almost identical to natural beta cells. This brings them a major step closer ...
Cell & Microbiology
Apr 11, 2016
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981
An international team of researchers from the Duke-NUS Medical School (Duke-NUS), the University of Bristol, Monash University and RIKEN have developed an algorithm that can predict the factors required to convert one human ...
Biotechnology
Jan 18, 2016
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47
Induced pluripotent stem cells (iPSCs)—adult cells reprogrammed back to an embryonic stem cell-like state—may better model the genetic contributions to each patient's particular disease. In a process called cellular reprogramming, ...
Biotechnology
Mar 25, 2015
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312
In a groundbreaking study that provides scientists with a critical new understanding of stem cell development and its role in disease, UCLA researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem ...
Cell & Microbiology
Jan 6, 2015
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176