Toward new drugs that turn genes on and off

Scientists in Michigan and California are reporting an advance toward development of a new generation of drugs that treat disease by orchestrating how genes in the body produce proteins involved in arthritis, cancer and a ...

New tool helps decipher gene behavior

Scientists have extensively researched the structure and sequence of genetic material and its interactions with proteins in the hope of understanding how our genetics and environment interact with diseases. This research ...

Decoding the molecular networks of early human development

New international research shines a light on the role of transcription factors during early embryonic development. Transcription factors are proteins that are critical for gene regulation. The study unveiled more than 1,000 ...

Elucidation of proteins controlling the sleep and awake transition

Professor Hiroki Ueda, Assistant Professor Daisuke Tone, Lecturer Koji Ode, and Qianhui Zhang (4th-year graduate student at the time) at the University of Tokyo showed that CaMKIIβ, a predominant protein kinase expressed ...

Scientists investigate epigenetic impact across whole genome

All life depends on a genome, which acts as an instruction manual for building all the products essential for development and survival. But knowing which of these individual instructions—or genes—need to be read, and ...

Droplets are key to cells' dynamic activities

A cell is a complex machine whose flexible architecture enables it to take part in life's activities: relaying information, managing waste, responding to stress.

Putting a finger on plant stress response

Post-translational modification is the process whereby proteins are modified after their initial biosynthesis. Modification can take many forms, including enzymatic cleavage of the protein or the addition of sugars, lipids, ...

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