With increasing age, and especially in neurodegenerative diseases such as Alzheimer's, proteins tend to misfold and aggregate into harmful deposits both inside and outside cells. Secreted proteins play an important role in ...
Cell & Microbiology
Jul 9, 2020
0
13
New images of an enzyme in action as it interacts with the chromosome could provide important insight into how cells—including cancer cells—regulate their genes.
Molecular & Computational biology
Jun 4, 2020
0
113
Bacteria have a cunning ability to survive in unfriendly environments.
Molecular & Computational biology
May 29, 2020
0
152
IMP scientists from the lab of Alexander Stark show why certain activators—enhancers or cofactor proteins—activate specific promoters. The findings, which are now reported in the journal Nature, could have implications ...
Biotechnology
May 16, 2019
0
83
Scientists have captured the first "snapshot" of two proteins involved in delivering a bacterial stress-response master regulator to the cell's recycling machinery.
Molecular & Computational biology
Apr 11, 2019
0
71
Pathological infertility is a condition affecting roughly 7 percent of human males, and among those afflicted, 10 to 15 percent are thought to have a genetic cause. However, pinpointing the precise genes responsible for the ...
Cell & Microbiology
Mar 26, 2019
0
23
Researchers at the University of Dundee have provided important new insights into the regulation of cell division, which may ultimately lead to a better understanding of cancer progression.
Cell & Microbiology
Mar 14, 2019
0
31
Transcription activator-like effector (TALE) proteins can be designed to bind to almost any selected DNA. Researchers now report that a TALE can displace another TALE protein from DNA in a highly polarized way – it can ...
Cell & Microbiology
Nov 26, 2018
0
27
Proteins are the building blocks of the cell. They do most of the work and are essential for the structure, function and dynamic regulation of the cell and body's tissues and organs. Proteins rarely work alone, they interact, ...
Cell & Microbiology
Oct 26, 2018
4
130
Walter and Eliza Hall Institute researchers have made a surprise discovery about how subtle changes in the way cell survival is regulated during embryonic development can have drastic health implications.
Cell & Microbiology
Sep 19, 2018
0
19
