Investigators from the laboratory of Ali Shilatifard, Ph.D., the Robert Francis Furchgott Professor and chair of Biochemistry and Molecular Genetics, have discovered a new repeat gene cluster sequence that is exclusively ...
Evolution
Nov 24, 2023
0
260
DNA and RNA, the two main types of nucleic acid and the building blocks of life, are susceptible to environmental stimuli, which can cause them to deform, bend or twist. These deformations can significantly affect gene regulation ...
Molecular & Computational biology
Aug 24, 2023
0
202
In multicellular organisms, all cells of an individual normally contain the same genetic information and cell differentiation is achieved through regulation of gene expression. There are exceptions, however, where, instead ...
Evolution
Aug 9, 2023
0
37
Plants have the unique ability to regenerate entirely from a somatic cell, i.e., an ordinary cell that does not typically participate in reproduction. This process involves the de novo (or new) formation of a shoot apical ...
Plants & Animals
Jul 7, 2023
0
351
Metabolic reaction flux change is the final result of interacting regulations by intracellular gene expression, transcriptional regulation, protein level, translation modification, and allosteric effect. However, the regulatory ...
Cell & Microbiology
Jun 20, 2023
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51
CTCF is a critical protein known to play various roles in key biological processes such as transcription. Scientists at St. Jude Children's Research Hospital have used a next-generation protein degradation technology to study ...
Biotechnology
Jan 25, 2023
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22
Inside cells, proteins constantly interact with each other to carry out different functions. For some diseases in which these functions are altered, blocking the binding between two or more proteins emerges as a possible ...
Biotechnology
Nov 30, 2022
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18
For four decades, Specificity Protein 1 (Sp1) has been cast solely as a transcription factor, a type of protein that binds DNA and turns genes on. But a Donnelly Center study has now revealed that Sp1 plays another unexpected ...
Cell & Microbiology
Sep 6, 2022
0
34
Chemotherapy sucks. The treatments generally have awful side effects, and it's no secret that the drugs involved are often toxic to the patient as well as their cancer. The idea is that, since cancers grow so quickly, chemotherapy ...
Biochemistry
Aug 24, 2022
0
119
In almost every human cell, 2 meters of DNA has to fit within a nucleus that is just 8 millionths of a meter wide. Like wool around a spool, the extreme space challenge requires DNA to wrap around structural proteins called ...
Evolution
Jun 9, 2022
0
47
