DNA and RNA, the two main types of nucleic acid and the building blocks of life, are susceptible to environmental stimuli, which can cause them to deform, bend or twist. These deformations can significantly affect gene regulation ...
Molecular & Computational biology
Aug 24, 2023
0
202
In multicellular organisms, all cells of an individual normally contain the same genetic information and cell differentiation is achieved through regulation of gene expression. There are exceptions, however, where, instead ...
Evolution
Aug 9, 2023
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37
Plants have the unique ability to regenerate entirely from a somatic cell, i.e., an ordinary cell that does not typically participate in reproduction. This process involves the de novo (or new) formation of a shoot apical ...
Plants & Animals
Jul 7, 2023
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351
Metabolic reaction flux change is the final result of interacting regulations by intracellular gene expression, transcriptional regulation, protein level, translation modification, and allosteric effect. However, the regulatory ...
Cell & Microbiology
Jun 20, 2023
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51
CTCF is a critical protein known to play various roles in key biological processes such as transcription. Scientists at St. Jude Children's Research Hospital have used a next-generation protein degradation technology to study ...
Biotechnology
Jan 25, 2023
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22
The study of microRNAs (miRNAs), small RNAs that play important roles in gene regulation in animals and humans alike, have long been a topic of research interest. How these miRNAs control and regulate gene expression is believed ...
Molecular & Computational biology
Jan 20, 2023
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12
MicroRNAs (miRNA) are small non-coding RNAs that regulate almost all biological processes, protein production, inflammatory responses, immune regulation, tumorigenesis and infection. In mammals, the classic formation of miRNA ...
Cell & Microbiology
Jan 17, 2023
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9
Inside cells, proteins constantly interact with each other to carry out different functions. For some diseases in which these functions are altered, blocking the binding between two or more proteins emerges as a possible ...
Biotechnology
Nov 30, 2022
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18
Professor Hiroki Ueda, Assistant Professor Daisuke Tone, Lecturer Koji Ode, and Qianhui Zhang (4th-year graduate student at the time) at the University of Tokyo showed that CaMKIIβ, a predominant protein kinase expressed ...
Molecular & Computational biology
Oct 26, 2022
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7
For four decades, Specificity Protein 1 (Sp1) has been cast solely as a transcription factor, a type of protein that binds DNA and turns genes on. But a Donnelly Center study has now revealed that Sp1 plays another unexpected ...
Cell & Microbiology
Sep 6, 2022
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